What Is Methylation?
Methylation is involved in how your DNA processes your genes. Methyl groups have a methyl group (single carbon, three hydrogen) to add another molecule. Methylation is critical for building, maintaining and repairing cells and tissues throughout the body. The methylation pathway is involved in one 200 enzymatic reactions downstream in the body.
Why Is Methylation
Role of methylation:
- Turning genes on and off needed
- Produces and metabolizes neurotransmitters, such as dopamine, serotonin, melatonin and epinephrine
- Protects DNA, nerve cells,
Builds immune cells (NK cells, neutrophils, eosinophils)
How Is Methylation Disrupted?
Methylation can be disrupted through:
- Malnutrition – Lack of required cofactors (folate, zinc, vitamin B2, B6, B12, magnesium or cysteine)
- Genetic mutations – Genetic mutation or polymorphisms for specific genes such as MTHFR, COMT, MAO and more) can impair the way you absorb methyl groups from your diet
- Drugs and Alcohol – Certain medication, drugs, and alcohol can impact methylation
- Environmental Toxicity – from heavy metal toxicity
- Gut Dysbiosis – Overgrowth of certain gut bacteria produces metabolites that affect the genes involved in methylation
What happens when Methylation is Disrupted?
Certain conditions are associated with poor methylation
- Anxiety
- Autism Spectrum
- Disorder
- Attention Deficit
- Hyperactivity Disorder (ADHD)
- Insomnia
- Cardiovascular disease
- Chronic infections
- Cancer
- Frequent infections
- Allergies
Treatment
The Natural Care Clinic uses lab testing and natural and holistic treatment plans to support your methylation pathway. Contact the Natural Care Clinic if you would like to book an appointment for methylation testing.
Phone: 905-631-0880
Email: info@naturalcareclinic.ca