Postural Orthostatic Tachycardia Syndrome (POTS) is a condition that affects circulation and blood flow and is classified as a form of dysautonomia. Dysautonomia is an umbrella term describing disorders of the autonomic nervous system and affects over 70 million people in North America.

The autonomic nervous system controls many vital functions we do not consciously regulate, including heart rate, blood pressure, digestion, temperature control, kidney function, pupil dilation, and the balance between the sympathetic (“fight or flight”) and parasympathetic (“rest and digest”) nervous systems. In POTS, this system does not regulate blood flow and heart rate appropriately when moving from lying or sitting to standing.

As a result, individuals experience an exaggerated increase in heart rate upon standing, often accompanied by a wide range of neurological, cardiovascular, and gastrointestinal symptoms.

Naturopathic Approach To POTS

Comprehensive Intake and Assessment

A detailed intake is essential to understand the type and drivers of POTS in each individual. This includes:

  • Symptom history, onset, and triggers (infection, stress, hormonal changes, trauma)
  • Assessment of dizziness, fatigue, brain fog, headaches, migraines, and sleep disturbances
  • Evaluation of pain patterns, including neuropathic pain and abdominal discomfort
  • Review of gastrointestinal symptoms such as gastroparesis or rapid gastric emptying
  • Screening for connective tissue disorders, mast cell activation, and autoimmune conditions
  • Assessment of hydration status, salt intake, and blood volume
  • Review of medications, supplements, and stimulant exposure
  • Evaluation of nervous system tone and stress response

POTS is not a single condition but a spectrum of autonomic dysfunction, and identifying contributing patterns is critical.

Comprehensive Functional Testing

Testing is used to confirm POTS and identify underlying contributors. This may include:

Orthostatic Heart Rate Assessment

Heart rate is measured in different positions:

  • Lying down
  • Seated
  • Standing

Heart rate should remain relatively stable between positions. An increase of 20–30 beats per minute or more upon standing is consistent with Postural Orthostatic Tachycardia Syndrome.

Additional Functional Testing May Include:

  • Nutrient assessments (B vitamins, magnesium, carnitine, CoQ10)
  • Inflammatory and immune markers
  • Evaluation for mast cell activation
  • Adrenal and stress-response testing
  • Digestive function testing
  • Assessment of microcirculation and mitochondrial health

These findings help determine which subtype of POTS is present and guide treatment priorities.

Individualized Treatment Plan

The biomedical naturopathic approach to POTS focuses on stabilizing circulation, calming the nervous system, and improving cellular energy and blood flow. Treatment is always individualized and may address one or more POTS patterns:

Hypovolemic (Low Blood Volume) POTS

  • Increased salt and fluid intake
  • Electrolyte support
  • Nutrients that support blood volume regulation

Inflammatory or Vascular Dysfunction

  • Support for blood vessel inflammation and reactivity
  • Nutrients such as zinc and quercetin (immunophore support)
  • Antihistamine strategies when appropriate
  • Support similar to conditions involving vascular spasm (e.g., Raynaud’s-type responses)

Hyperadrenergic POTS

  • Nervous system calming strategies
  • Magnesium, vitamin B12, and targeted herbal supports
  • Stress-response and adrenal regulation

 

Microcirculatory Dysfunction

  • Support for blood flow at the capillary level
  • Vitamin E, Coenzyme Q10, carnitine
  • Microcirculation-supporting botanical medicines

Neurogenic POTS

  • Targeted B-vitamin support (especially B1 and B12)
  • Sulfate and electrolyte balance
  • Mitochondrial and nerve-supportive nutrients

Biomedical treatment for POTS is not a quick fix. It is a gradual, step-by-step process aimed at restoring autonomic balance, improving circulation, and increasing resilience. Over time, individualized care often leads to improved tolerance to standing, reduced symptom burden, and better quality of life.