Histamine Testing

In histamine intolerance (HIT), the impairment of GI histamine degradation causes functional, nonspecific, non-allergic GI complaints and extra-intestinal complaints

An unbalanced and elevated quantity of histamine in HIT seems to be the main consequence of the ingestion of histamine-containing foods.

Predominantly, in HIT, the intestinal enzyme diamine oxidase (DAO) has a reduced ability to metabolize and degrade histamine.